abstract：:Pediatric neuro-oncology surgery continues to progress in sophistication, largely driven by advances in technology used to aid the following aspects of surgery: operative planning (advanced MRI techniques including fMRI and DTI), intraoperative navigation [preoperative MRI, intra-operative MRI (ioMRI) and intra-operat...

journal_title：Frontiers in pediatrics

authors： Foster MT,Harishchandra LS,Mallucci C

更新日期：2018-11-01 00:00:00

abstract：:Background: Childhood refractory mycoplasma pneumoniae (MP) pneumonia (RMPP) is a lung disease with elevated level of C-reactive protein and severe clinical and radiological deterioration. Whether bacterial co-infection contributes to disease of RMPP and whether inclusion of non-anti-MP antibiotics in treatment regime...

journal_title：Frontiers in pediatrics

authors： Liu JR,Lu J,Dong F,Li HM,Liu H,Tang XL,Guo YL,Zhao SY

更新日期：2018-10-26 00:00:00

abstract：:Deficiency of adenosine deaminase 2 (DADA2) is a monogenic form of systemic vasculopathy that often presents during early childhood. Linked to biallelic mutations in ADA2 (previously CECR1), DADA2 was initially described as a syndrome of recurrent fever, livedo racemosa, early-onset strokes, and peripheral vasculopath...

journal_title：Frontiers in pediatrics

authors： Lee PY

更新日期：2018-10-18 00:00:00

abstract：:Objectives: Severe congenital neutropenia (SCN) is a primary immunodeficiency disease characterized by the early onset of recurrent infections and persistent severe neutropenia, with or without genetic defect. We aimed to study the different clinical features and hematological and bone marrow characteristics of patien...

journal_title：Frontiers in pediatrics

authors： Gong RL,Wu J,Chen TX

更新日期：2018-10-16 00:00:00

abstract：:Introduction: Childhood obesity is occurring at alarming rates in both developed and developing countries. "Obesogenic" environmental factors must be associated with variants of different risk alleles to determine polygenic or common obesity, and their impact depends on different developmental stages.The interaction b...

journal_title：Frontiers in pediatrics

authors： Mǎrginean CO,Mǎrginean C,Meliţ LE

更新日期：2018-10-04 00:00:00

abstract：:We describe a previously healthy 14-year-old girl with acute onset autoimmune hemolytic anemia, associated with severe but transient lymphopenia during corticosteroid therapy, without infectious episodes during follow-up. After detailed investigations to rule out an underlying immunodeficiency, we detected a heterozyg...

journal_title：Frontiers in pediatrics

authors： Tripodi SI,Corti P,Giliani S,Lanfranchi A,Biondi A,Badolato R

更新日期：2018-10-01 00:00:00

abstract：:Objective: In many patients with congenital heart disease (CHD) arterial blood flow to the arms is inhibited due to shunt surgery in infancy. This study investigates the handgrip strength of patients with CHD in regard to previous shunt procedures. Patients and Methods: Handgrip was evaluated in 424 patients with vari...

journal_title：Frontiers in pediatrics

authors： Müller J,Röttgers L,Neidenbach RC,Oberhoffer R,Ewert P,Hager A

更新日期：2018-09-06 00:00:00

abstract：:Introduction: Decreased respiratory muscle strength in patients with cystic fibrosis (CF) may cause progressive exercise intolerance during cardiopulmonary exercise testing (CPET), and may contribute to the development of chronic respiratory insufficiency. The aim of this study is to evaluate exercise tolerance during...

journal_title：Frontiers in pediatrics

authors： Sovtic A,Minic P,Markovic-Sovtic G,Trajkovic GZ

更新日期：2018-09-04 00:00:00

abstract：:We report a novel homozygous JAK3 mutation in two female Brazilian SCID infants from two unrelated kindreds. Patient 1 was referred at 2 months of age due to a family history of immunodeficiency and the appearance of a facial rash. The infant was screened for TRECs (T-cell receptor excision circles) and KRECs (kappa-d...

journal_title：Frontiers in pediatrics

authors： Barreiros LA,Segundo GRS,Grumach AS,Roxo-Júnior P,Torgerson TR,Ochs HD,Condino-Neto A

更新日期：2018-08-20 00:00:00

abstract：:Background: Although WU polyomavirus (WU) and KI polyomavirus (KI) have been demonstrated to infect the human respiratory tract, it remains unclear if WU or KI cause human disease. We sought to further investigate the relationship between WU and KI infection and respiratory disease in a pediatric population with respi...

journal_title：Frontiers in pediatrics

authors： Hansen-Estruch C,Coleman KK,Thoon KC,Low JG,Anderson BD,Gray GC

更新日期：2018-08-17 00:00:00

abstract：:Introduction: Hemolytic-uremic syndrome (HUS) is a common cause for intrarenal acute kidney injury in childhood. More than 90% of HUS cases are associated with an infection by Shigatoxin-producing Escherichia coli (STEC) whereas the reminder comprises a heterogeneous group (here classified as Non-STEC-HUS). Renal impa...

journal_title：Frontiers in pediatrics

authors： Vaterodt L,Holle J,Hüseman D,Müller D,Thumfart J

更新日期：2018-08-07 00:00:00

abstract：:The term osteopetrosis describes a group of rare hereditary diseases of the skeleton, characterized by an increase in bone density, caused by a defect in the development or function of osteoclasts. It comprises a clinically and genetically heterogeneous conditions ranging from infantile onset life-threatening forms to...

journal_title：Frontiers in pediatrics

authors： di Palmo E,Gallucci M,Tronconi E,Bergamaschi R,Cazzato S,La Scola C,Ricci G,Pession A

更新日期：2018-07-31 00:00:00

abstract：:The burden of severe hearing impairment is increasing with two-thirds of these hearing impaired people residing in developing countries. Newborn hearing screening helps to identify early, babies who need intervention in order to prevent future disability. Neither universal nor targeted hearing screening programme is a...

journal_title：Frontiers in pediatrics

authors： Labaeka AA,Tongo OO,Ogunbosi BO,Fasunla JA

更新日期：2018-07-16 00:00:00

abstract：:Lung function is an important tool in the diagnosis and monitoring of patients with asthma at all ages. Airway obstruction is a typical feature of asthma and it can be assessed with several lung function techniques. Spirometry, respiratory resistance and reactance, and lung volumes are available to measure it at diffe...

journal_title：Frontiers in pediatrics

authors： Calogero C,Fenu G,Lombardi E

更新日期：2018-06-26 00:00:00

abstract：:Objective: Magnetic resonance imaging (MRI) and cardiac catheterization are diagnostic tools for right ventricle dysfunction (RVD), but those are expensive and often unavailable techniques. Thus, our objective was to identify clinical and/or echocardiographic variables capable of predicting a catheterization-based dia...

journal_title：Frontiers in pediatrics

authors： Márquez-González H,Vargas MH,Yáñez-Gutiérrez L,Almeida-Gutiérrez E,Garduño-Espinosa J

更新日期：2018-06-26 00:00:00

abstract：:Asthma is the most common chronic disease in children, imposing a consistent burden on health system. In recent years, prevalence of asthma symptoms became globally increased in children and adolescents, particularly in Low-Middle Income Countries (LMICs). Host (genetics, atopy) and environmental factors (microbial ex...

journal_title：Frontiers in pediatrics

authors： Ferrante G,La Grutta S

更新日期：2018-06-22 00:00:00

abstract：:Introduction: Ventilation causes cerebral white matter inflammation and injury, which is exacerbated by intrauterine inflammation. However, the effects on cortical gray matter are not well-known. Our aim was to examine the effect of ventilation on the cerebral cortex of near-term lambs exposed to intrauterine inflamma...

journal_title：Frontiers in pediatrics

authors： Stojanovska V,Atik A,Nitsos I,Skiöld B,Barton SK,Zahra VA,Rodgers K,Hooper SB,Polglase GR,Galinsky R

更新日期：2018-06-15 00:00:00

abstract：:Objectives: Low hydration has a deleterious effect on many conditions. In the absence of a urine concentrating defect, urine concentration is a marker of hydration status. However, markers to evaluate hydration status have not been well studied in children. The objectives of this paper are to compare measures of thirs...

journal_title：Frontiers in pediatrics

authors： Walawender L,Patterson J,Strouse R,Ketz J,Saxena V,Alexy E,Schwaderer A

更新日期：2018-06-06 00:00:00

abstract：:Segmental colitis associated with diverticulosis (SCAD) is manifested by active chronic inflammation of the colonic segments affected by diverticulosis, luminal-mucosal inflammation, independent of the presence of inflammation within and/or around the diverticula, and it usually spares the rectum. We present the case ...

journal_title：Frontiers in pediatrics

authors： Mǎrginean CO,Meliţ LE,Mǎrginean MO

更新日期：2018-06-05 00:00:00

abstract：:Introduction: Autosomal recessive polycystic kidney disease (ARPKD) is a severe hepatorenal disorder of childhood. Early renal disease in ARPKD may require renal replacement therapy and is associated with failure to thrive resulting in a need for nasogastric tube feeding or gastrostomy. In ARPKD patients, the benefit ...

journal_title：Frontiers in pediatrics

authors： Burgmaier K,Brandt J,Shroff R,Witters P,Weber LT,Dötsch J,Schaefer F,Mekahli D,Liebau MC

更新日期：2018-06-04 00:00:00

abstract：:Perianal abscess and fistula-in-ano are well-described in the pediatric population. They are most common in infants less than 1 year of age and often resolve with oral antibiotics; occasionally they require drainage or fistulotomy. The etiology is commonly associated with cryptoglandular obstruction and subsequent inf...

journal_title：Frontiers in pediatrics

authors： Barry WE,Asuelime GE,Zhou S,Hammoudeh J,Ford HR,Kim ES

更新日期：2018-05-16 00:00:00

abstract：:Background: This paper presents design and results from preliminary evaluation of Tangible Geometric Games (TAG-Games) for cognitive assessment in young children. The TAG-Games technology employs a set of sensor-integrated cube blocks, called SIG-Blocks, and graphical user interfaces for test administration and real-t...

journal_title：Frontiers in pediatrics

authors： Lee K,Jeong D,Schindler RC,Hlavaty LE,Gross SI,Short EJ

更新日期：2018-05-08 00:00:00

abstract：:Background: Oral health is important for overall health of youth, although dental service utilization is lower than national goals. The purpose of the study was to identify sociodemographic and health behavioral characteristics of youth in the United States who reported having at least one dental visit in the past 12 ...

journal_title：Frontiers in pediatrics

authors： Chertok IRA,Chertok N,Haile ZT,Chavan B

更新日期：2018-05-04 00:00:00

abstract：:Fetal sex is associated with striking differences during in utero development, fetal-to-neonatal transition, and postnatal morbidity and mortality. Male sex fetuses are apparently protected while in utero resulting in a higher secondary sex rate for males than for females. However, during fetal-to-neonatal transition ...

journal_title：Frontiers in pediatrics

authors： Lorente-Pozo S,Parra-Llorca A,Torres B,Torres-Cuevas I,Nuñez-Ramiro A,Cernada M,García-Robles A,Vento M

更新日期：2018-04-23 00:00:00

abstract：Objectives:Disparities in obesity care exist among African-American children and adults. We sought to test the feasibility of a pilot program, a 1-year family-based intervention for African-American families with obesity [shape up and eat right (SUPER)], adopting the shared medical appointment model (SMA) at an urban s...

journal_title：Frontiers in pediatrics

authors： Srivastava G,Palmer KD,Ireland KA,McCarthy AC,Donovan KE,Manders AJ,McDougal J,Lenders CM,Apovian CM

更新日期：2018-04-12 00:00:00

abstract：:Since the advent of extracorporeal membrane oxygenation (ECMO) over 40 years ago, there has been increasing interest in the use of the extracorporeal circuit as a platform for providing multiple organ support. In this review, we will examine the evidence for the use of continuous renal replacement therapy, therapeutic...

journal_title：Frontiers in pediatrics

authors： Canter MO,Daniels J,Bridges BC

更新日期：2018-04-03 00:00:00

abstract：:Pediatric critical care services in India have grown with leaps and bounds. There has been a growing need of physicians specially trained in pediatric critical care medicine (PCCM) in India. Physicians returning to India after their formal training in PCCM abroad have partly supported this growing need. Development of...

journal_title：Frontiers in pediatrics

authors： Bhalala U,Khilnani P

更新日期：2018-02-26 00:00:00

abstract：Background:This study aimed to assess the prevalence of picky eating among preschool children and to evaluate the association between eating behavior and growth, physical activity, development, and health status. Methods:A structured questionnaire was used to conduct a cross-sectional descriptive study of 300 primary ...

journal_title：Frontiers in pediatrics

authors： Chao HC

更新日期：2018-02-12 00:00:00

abstract：:The glomerular basement membrane (GBM) is a specialized structure with a significant role in maintaining the glomerular filtration barrier. This GBM is formed from the fusion of two basement membranes during development and its function in the filtration barrier is achieved by key extracellular matrix components inclu...

journal_title：Frontiers in pediatrics

authors： Chew C,Lennon R

更新日期：2018-01-29 00:00:00

abstract：:Pontocerebellar hypoplasia (PCH) type 2 is a very rare autosomal recessive neurodegenerative disorder with prenatal onset that disrupts brain development. We present three patients (two siblings and one unrelated child) with PCH 2 linked to the most common mutation c.919G > T (p.Ala307Ser) in TSEN54 gene. The disease ...

journal_title：Frontiers in pediatrics

authors： Pacheva IH,Todorov T,Ivanov I,Tartova D,Gaberova K,Todorova A,Dimitrova D

更新日期：2018-01-23 00:00:00

abstract：:The use of prolonged respiratory support under the form of high-flow nasal cannula (HFNC) or nasal continuous positive airway pressure (nCPAP) is frequent in newborn infants. Introduction of oral feeding under such nasal respiratory support is, however, highly controversial among neonatologists, due to the fear that i...

journal_title：Frontiers in pediatrics

authors： Samson N,Nadeau C,Vincent L,Cantin D,Praud JP

更新日期：2018-01-17 00:00:00

abstract：Background:Given the positive influence of responsive caregiving on dietary habits in childhood, to raise awareness of caregivers regarding their behavior is crucial in multidisciplinary care on infant feeding. Objectives:To identify the most common responsive and non-responsive feeding practices in mothers of childre...

journal_title：Frontiers in pediatrics

authors： Machado RHV,Tosatti AM,Malzyner G,Maximino P,Ramos CC,Bozzini AB,Ribeiro L,Fisberg M

更新日期：2018-01-04 00:00:00

abstract：Background:Pediatric sepsis causes significant global morbidity and mortality and low- and middle-income countries (LMICs) bear the bulk of the burden. International sepsis guidelines may not be relevant in LMICs, especially in sub-Saharan Africa (SSA), due to resource constraints and population differences. There is a...

journal_title：Frontiers in pediatrics

authors： Kortz TB,Sawe HR,Murray B,Enanoria W,Matthay MA,Reynolds T

更新日期：2017-12-22 00:00:00

abstract：:Autosomal dominant polycystic kidney disease (ADPKD) affects 1 in 400 to 1,000 live births, making it the most common monogenic cause of renal failure. Although no definite cure is available yet, it is important to affect disease progression by influencing modifiable factors such as hypertension and proteinuria. Besid...

journal_title：Frontiers in pediatrics

authors： De Rechter S,Breysem L,Mekahli D

更新日期：2017-12-20 00:00:00

abstract：Aim:The purpose of this study is to describe the development of an external 3-dimensional (3D) scanner as a noninvasive method for imaging chest wall deformities. It allows objective assessment, reconstruction of the area of interest, and evaluation of the severity of the deformity by using external indexes. External ...

journal_title：Frontiers in pediatrics

authors： Lain A,Garcia L,Gine C,Tiffet O,Lopez M

更新日期：2017-12-04 00:00:00

abstract：:Acute myeloid leukemia (AML) is the second most common leukemia of childhood and is associated with high rates of chemotherapy resistance and relapse. Clinical outcomes for children with AML treated with maximally intensive multi-agent chemotherapy lag far behind those of children with the more common acute lymphoblas...

journal_title：Frontiers in pediatrics

authors： Sexauer AN,Tasian SK

更新日期：2017-11-20 00:00:00

abstract：Background:Acute respiratory illnesses with cough (ARIwC) are predominant causes of morbidity in Australian Indigenous children; however, data on disease burden in urban communities are scarce. This study aimed to determine the incidence of ARIwC, the predictors of recurrent (≥4 episodes) ARIwC, and development of chro...

journal_title：Frontiers in pediatrics

authors： Hall KK,Chang AB,Anderson J,Arnold D,Goyal V,Dunbar M,Otim M,O'Grady KF

更新日期：2017-10-31 00:00:00

abstract：BACKGROUND:Acute gastroenteritis (AGE) causing dehydration with or without dysnatremias is a common childhood health challenge. While it is accepted that oral rehydration therapy is preferred, clinical factors or parent and healthcare provider preferences may lead to intravenous rehydration (IVR). Isotonic solutions ar...

journal_title：Frontiers in pediatrics

authors： Grisaru S,Xie J,Samuel S,Freedman SB

更新日期：2017-10-06 00:00:00

abstract：:Sensory processing difficulties are common among many special needs children, especially those with autism spectrum disorder (ASD). The sensory sensitivities often result in interference of daily functioning and can lead to social isolation for both the individual and family unit. A quality improvement (QI) project wa...

journal_title：Frontiers in pediatrics

authors： Kong M,Pritchard M,Dean L,Talley M,Torbert R,Maha J

更新日期：2017-09-15 00:00:00

abstract：:[This corrects the article on p. 82 in vol. 5, PMID: 28484690.]. ...

journal_title：Frontiers in pediatrics

authors： Tsabouri S,Mavroudi A,Feketea G,Guibas GV

更新日期：2017-09-11 00:00:00